During periods of epidemics humans are the reservoir of the virus. E1 contains a fusion peptide which, when exposed to the acidity of the endosome in eukaryotic cells , dissociates from E2 and initiates membrane fusion that allows the release of nucleocapsids into the host cytoplasm, promoting infection. This page was last edited on 4 November , at Retrieved 13 June
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South African medical [Suid-Afrikaanse tydskrif vir geneeskunde]. Archived from the original on 18 May Archived from the original on 18 September Archived from the original on 19 December The erroneous attribution to Swahili has been repeated in numerous print sources. Global Strategy for Dengue Control Dr. Get plenty of rest.
No antiviral treatment for chikungunya virus is currently available, though testing has shown several medications to be effective in vitro. Estimated number of dengue infections each year — Learn more. The inflammation response during both the acute and chronic phase of the disease results in part from interactions between the virus and monocytes and macrophages.
Symptoms, Diagnosis, & Treatment
See your healthcare provider if you develop the symptoms described pehyakit and have visited an area where chikungunya is found. The mortality rate of chikungunya is slightly less than 1 in Archived copy as title Webarchive template wayback links Use dmy dates from March Infobox medical condition new Articles with 'species' microformats Articles containing potentially dated statements from All articles containing potentially dated statements Requests for audio cyikungunya English RTT RTTID.
Archived from the original on 5 May The Journal of Experimental Medicine. Markers of autoimmune or rheumatoid disease have not been found in people reporting chronic symptoms.
Skip directly to search Skip directly to A to Z list Skip directly to navigation Skip directly to page options Skip directly to site content. Aedes albopictus and Aedes aegypti. Fever occurs with the onset of viremia, and the level of virus in the blood correlates with the intensity of symptoms in the acute phase. Rodent-borne Arenaviridae Viral hemorrhagic fevers: Archived from the original PDF on 19 October Archived from the original on 22 February The first recorded outbreak of this disease may have been in Archived from the original on 19 August Other arbo-viral diseases Neglected tropical diseases Vector ecology pwnyakit management.
Symptoms, Diagnosis, & Treatment | Chikungunya virus | CDC
The disease causes an estimated 3 million infections each year. The word 'chikungunya' is believed to have been derived from a description in the Makonde language, meaning "that which bends up", of the contorted chikhngunya of people affected with the severe joint pain and arthritic symptoms associated with this disease.
Archived from the original on 21 September Archived from the original on 27 February Other symptoms may include headache, muscle pain, joint swelling, or rash. Cytokines may also contribute to chronic chikungunya virus disease, as persistent joint pain has been associated with elevated levels of IL-6 and granulocyte-macrophage colony-stimulating factor GM-CSF. General description and epidemiology". E1 contains a fusion peptide which, when exposed to the acidity of the endosome in eukaryotic cellsdissociates from E2 and initiates membrane fusion that allows the release of nucleocapsids into the host cytoplasm, promoting infection.
Local transmission has also occurred in the United States and Australia, countries in which the virus was previously unknown. Current Infectious Disease Reports.